Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms 		0.300 Biomarker phenotype CTD_human Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. 18184829 2008
CUI: C0042571
Disease: Vertigo
Vertigo 		0.010 Biomarker phenotype BEFREE Individuals with the minor allele of CHRNB2 variants experienced less nausea than did those without the minor allele, consistent with previously reported findings for CHRNB2 and the occurrence of nausea and dizziness as a consequence of first smoking attempt in adolescents, and with the known neurophysiology of nausea. 21606948 2012
CUI: C0038644
Disease: Sudden infant death syndrome
Sudden infant death syndrome 		0.300 Biomarker disease CTD_human Effects of cigarette smoke exposure on nicotinic acetylcholine receptor subunits α7 and β2 in the sudden infant death syndrome (SIDS) brainstem. 22000980 2011
CUI: C0751511
Disease: Subwakefullness Syndrome
Subwakefullness Syndrome 		0.300 Biomarker phenotype CTD_human beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. 12228730 2002
CUI: C0038587
Disease: Substance Withdrawal Syndrome
Substance Withdrawal Syndrome 		0.300 Biomarker disease CTD_human Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. 18184829 2008
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.010 Biomarker disease BEFREE These results indicate that some genes (TP53, CCDC151, CHRNB2, GMPR2, HDGFRP2, VSTM2L) and previously unidentified signaling pathways (eg, the Hippo signaling pathway) might play an important role in H. pylori-associated GC. 30175534 2018
CUI: C0751510
Disease: Sleep-Related Neurogenic Tachypnea
Sleep-Related Neurogenic Tachypnea 		0.300 Biomarker phenotype CTD_human beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. 12228730 2002
CUI: C4042891
Disease: Sleep Wake Disorders
Sleep Wake Disorders 		0.300 Biomarker group CTD_human beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. 12228730 2002
CUI: C0851578
Disease: Sleep Disorders
Sleep Disorders 		0.300 Biomarker group CTD_human beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. 12228730 2002
CUI: C0751509
Disease: Short Sleeper Syndrome
Short Sleeper Syndrome 		0.300 Biomarker disease CTD_human beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. 12228730 2002
CUI: C0036572
Disease: Seizures
Seizures 		0.100 Biomarker phenotype HPO
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.320 Biomarker disease LHGDN Our present study provided the first line of direct evidence suggesting that the CHRNA4 gene combined with CHRNB2 receptor gene may be linked to schizophrenia. 16636791 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.320 Biomarker disease BEFREE Our results suggest that CHRNA4 and CHRNB2 do not play a major role in Japanese schizophrenia. 18762859 2008
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.320 Biomarker disease BEFREE Our present study provided the first line of direct evidence suggesting that the CHRNA4 gene combined with CHRNB2 receptor gene may be linked to schizophrenia. 16636791 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.320 Biomarker disease PSYGENET Our results suggest that CHRNA4 and CHRNB2 do not play a major role in Japanese schizophrenia. 18762859 2008
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.320 Biomarker disease PSYGENET Our present study provided the first line of direct evidence suggesting that the CHRNA4 gene combined with CHRNB2 receptor gene may be linked to schizophrenia. 16636791 2006
CUI: C0751481
Disease: Reflex, Triceps, Decreased
Reflex, Triceps, Decreased 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
CUI: C0558846
Disease: Reflex, Triceps, Absent
Reflex, Triceps, Absent 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
CUI: C0751480
Disease: Reflex, Triceps, Abnormal
Reflex, Triceps, Abnormal 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
CUI: C0277850
Disease: Reflex, Pendular
Reflex, Pendular 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
CUI: C0751479
Disease: Reflex, Moro, Asymmetric
Reflex, Moro, Asymmetric 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
CUI: C0751478
Disease: Reflex, Knee, Decreased
Reflex, Knee, Decreased 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
CUI: C0751477
Disease: Reflex, Knee, Abnormal
Reflex, Knee, Abnormal 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
CUI: C0751476
Disease: Reflex, Gag, Decreased
Reflex, Gag, Decreased 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013
CUI: C0234784
Disease: Reflex, Gag, Absent
Reflex, Gag, Absent 		0.300 Therapeutic phenotype CTD_human The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. 23419392 2013